[No.KKN-CSM-25] Atelocollagen sponge, MIGHTY (25 pcs)
A “physically strong” collagen sponge (96-well plate size) derived from bovine dermal type I collagen that shows resistance to compressive loading. Culturing with dynamic stimulus (such as pressure) can mimic in-vivo-like cell response as shown in some arthritic cell culture models.
Applications
- Cell culture under dynamic stimuli
- 3D cell culture
- Carrier for cell transplant
Features
- Retains structural rigidity during repeated compression loading of 10-20 kPa
- Sized for 96 well plates
Data
“Mechanical stimulus culture assay using MIGHTY.”
(K. Shimomura, K. Nakata et al. Osaka University, Faculty of Medicine)
Forty kPa of repeated compressive load for 1 hour induced the expression of PEG2, IL6 and IL8, which are correlated to arthritis, after three days cultivation on MIGHTY.
Dexamethasone (Dex), anti-inflammatory agent, reduced the expression of PEG2, IL6 and IL8 in a concentration-dependent manner. These results indicate MIGHTY can be used for in vitro arthritis models.
SPECIFICATION
Product Name
Atelocollagen sponge, MIGHTY
Catalog Number
KKN-CSM-25
KKN-CSM-50
Size
- 25 pieces
- 50 pieces
Sponge Dimensions
5 mm diameter × 3 mm sponges
Storage and Stability
Store at Room Temperature
Sterility
Sterile
Notice To Purchaser
REPROCELL is a licensed global distributor of KOKEN’s collagen-derived products everywhere, except for Japan.
Manufacturer
Koken Co., Ltd. (Japan)
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