In vivo transfection kit for siRNA and microRNA
Atelocollagen, the main component of AteloGene, forms RNA-atelocollagen complexes upon mixing with synthetic siRNA or miRNA. The RNA-atelocollagen complexes are optimal for in vivo transfection, and siRNA or miRNA is effectively delivered to, and introduced into the cells.
AteloGene Local Use Quick Gelation is limited to localized administration due to its gelation feature. Gelated siRNA/atelocollagen complexes remain at the injection site, allowing siRNA and miRNA to be delivered into the cells effectively. This “quick gelation” version of AteloGene is an improved version of the prior Atelogene kit (KKN-1394). The quick gelation kit offers a faster protocol and improved results.
AteloGene procedures are simple and easy — mix equal volumes of AteloGene and RNA solution, and administer the siRNA/miRNA AteloGene mixture to the mouse.
*1 Kit is sufficient for 15 injections (200 µL).